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Article

Mutation in ABCA1 predicted risk of ischemic heart disease in the Copenhagen City Heart Study Population.

Journal of the American College of Cardiology - 18 Oct 2005

Frikke-Schmidt Ruth, Nordestgaard Børge G, Schnohr Peter, Steffensen Rolf, Tybjaerg-Hansen Anne

Abstract excerpt

OBJECTIVES: We tested whether heterozygosity for the K776N mutation (frequency: 0.4%) in ATP-binding cassette transporter A1 (ABCA1) predicted ischemic heart disease (IHD) in the Copenhagen City Heart Study population. BACKGROUND: In a complex trait like IHD, genetic variation is considered to be conferred by common DNA polymorphisms, although rare mutations may have a larger impact. Tangier disease, a rare...

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Identifiers

PMID: 16226177
DOI: 10.1016/j.jacc.2005.06.066

Genes

ABCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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