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Article

Both PIGA and PIGL mutations cause GPI-a deficient isolates in the Tk6 cell line.

Environmental and molecular mutagenesis - 1 Oct 2015

Nicklas Janice A, Carter Elizabeth W, Albertini Richard J

Abstract excerpt

Molecular analysis of proaerolysin selected glycosylphosphatidylinositol anchor (GPI-a) deficient isolates in the TK6 cell line was performed. Initial studies found that the expected X-linked PIGA mutations were rare among the spontaneous isolates but did increase modestly after ethyl methane sul...

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Source

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Identifiers

PMID: 25970100
DOI: 10.1002/em.21953
PMCID: PMC4607541

Genes

GPI
PIGL
PIGA
NCOR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25970100-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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