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Article

PIG-A gene abnormalities in Thai patients with paroxysmal nocturnal hemoglobinuria.

The Southeast Asian journal of tropical medicine and public health - 1 Jan 1995

Pramoonjago P, Wanachiwanawin W, Chinprasertsuk S, Pattanapanyasat K, Takeda J, Kinoshita T

Abstract excerpt

Deficient biosynthesis of the glycosyl phosphatidyl inositol (GPI)-anchor in blood cells is implicated in the pathogenesis of paroxysmal nocturnal hemoglobinuria (PNH). Abnormal clonal cells appear in various hematopoietic cell lineages, suggesting that PNH arises as a result of somatic mutation occurred at the multipotential hematopoietic stem cell stage. We previously cloned a gene which is responsible for PNH....

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PMID: 8629134

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GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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PIG-A gene abnormalities in Thai patients with paroxysmal nocturnal hemoglobinuria.PMID 8629134Read ↗

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Characterization of genomic PIG-A gene: a gene for glycosylphosphatidylinositol-anchor biosynthesis and paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

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Somatic mutations of PIG-A in Thai patients with paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Somatic mutations of the PIG-A gene found in Japanese patients with paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Genotypic, immunophenotypic and clinical features of Thai patients with paroxysmal nocturnal haemoglobinuria.Semantic proximity Read ↗

Heterogeneous PIG-A mutations in different cell lineages in paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Abnormalities of PIG-A Transcripts in Granulocytes from Patients with Paroxysmal Nocturnal HemoglobinuriaSemantic proximity Read ↗

Mutation analysis of the PIG-A gene in Korean patients with paroxysmal nocturnal haemoglobinuria.Semantic proximity Read ↗

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