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Article

A novel candidate region for genetic adaptation to high altitude in Andean populations.

PloS one - 1 Jan 2015

Valverde Guido, Zhou Hang, Lippold Sebastian, de Filippo Cesare, Tang Kun, López Herráez David, Li Jing, Stoneking Mark

Abstract excerpt

Humans living at high altitude (≥ 2,500 meters above sea level) have acquired unique abilities to survive the associated extreme environmental conditions, including hypoxia, cold temperature, limited food availability and high levels of free radicals and oxidants. Long-term inhabitants of the most elevated regions of the world have undergone extensive physiological and/or genetic changes, particularly in the...

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PMID: 25961286
DOI: 10.1371/journal.pone.0125444
PMCID: PMC4427407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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