Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selection scan reveals three new loci related to high altitude adaptation in Native Andeans.

Scientific reports - 24 Aug 2018

Jacovas Vanessa C, Couto-Silva Cainã M, Nunes Kelly, Lemes Renan B, de Oliveira Marcelo Z, Salzano Francisco M, Bortolini Maria Cátira, Hünemeier Tábita

Abstract excerpt

The Andean Altiplano has been occupied continuously since the late Pleistocene, ~12,000 years ago, which places the Andean natives as one of the most ancient populations living at high altitudes. In the present study, we analyzed genomic data from Native Americans living a long-time at Andean high altitude and at Amazonia and Mesoamerica lowland areas. We have identified three new candidate genes - SP100, DUOX2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Altitude

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to American Indian or Alaska Native

Share to Genetic Loci

Share to Geography

Share to Homozygote

Share to Selection, Genetic

Share to South America

Source

Open in PubMed Open full text

Identifiers

PMID: 30143708
DOI: 10.1038/s41598-018-31100-6
PMCID: PMC6109162

Genes

CLC
DUOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selection scan reveals three new loci related to high altitude adaptation in Native Andeans.PMID 30143708Read ↗

A novel candidate region for genetic adaptation to high altitude in Andean populations.Semantic proximity Read ↗

Genetic Variations in the TP53 Pathway in Native Americans Strongly Suggest Adaptation to the High Altitudes of the Andes.Semantic proximity Read ↗

Exome sequencing reveals genetic differentiation due to high-altitude adaptation in the Tibetan cashmere goat (Capra hircus).Semantic proximity Read ↗

Genetic analysis of cold tolerance and high-altitude adaptation in Gannan indigenous Tibetan sheep through genome-wide scans.Semantic proximity Read ↗

Structural variant selection for high-altitude adaptation using single-molecule long-read sequencingSemantic proximity Read ↗

Identifying positive selection candidate loci for high-altitude adaptation in Andean populations.Semantic proximity Read ↗

Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data.Semantic proximity Read ↗

Uncovering Signals of Positive Selection in Peruvian Populations from Three Ecological Regions.Semantic proximity Read ↗

Genomic Insights into Tibetan Sheep Adaptation to Different Altitude Environments.Semantic proximity Read ↗

Seq-ing Higher Ground: Functional Investigation of Adaptive Variation Associated With High-Altitude AdaptationSemantic proximity Read ↗

Evolutionary significance of selected EDAR variants in Tibetan high-altitude adaptations.Semantic proximity Read ↗

Tibetan near-complete pangenome reveals complex variants underlying high-altitude adaptationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.