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Article

Evolutionary significance of selected EDAR variants in Tibetan high-altitude adaptations.

Science China. Life sciences - 1 Jan 2018

Shao Jianming, Raza Muhammad Sohail, Zhuoma Basang, Zeng Changqing

Abstract excerpt

Humans have been exposed to many environmental challenges since their evolutionary origins in Africa and subsequent migrations to the rest of the world. A severe environmental challenge to human migrants was hypoxia caused by low barometric oxygen pressure at high altitudes. Several genome-wide scans have elucidated the genetic basis of human high-altitude adaptations. However, the dearth of functional variant...

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Share to Acclimatization
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28795375
DOI: 10.1007/s11427-016-9045-7

Genes

EDAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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