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Article

Talin is required to position and expand the luminal domain of the Drosophila heart tube.

Developmental biology - 15 Sept 2015

Vanderploeg Jessica, Jacobs J Roger

Abstract excerpt

Fluid- and gas-transporting tubular organs are critical to metazoan development and homeostasis. Tubulogenesis involves cell polarization and morphogenesis to specify the luminal, adhesive, and basal cell domains and to establish an open lumen. We explore a requirement for Talin, a cytoplasmic integrin adapter, during Drosophila melanogaster embryonic heart tube development. Talin marks the presumptive luminal...

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PMID: 25958089
DOI: 10.1016/j.ydbio.2015.04.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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