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Article

Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila.

Nature cell biology - 1 May 2005

Bécam Isabelle E, Tanentzapf Guy, Lepesant Jean-Antoine, Brown Nicholas H, Huynh Jean-René

Abstract excerpt

The Drosophila melanogaster anterior-posterior axis becomes polarized early during oogenesis by the posterior localization of the oocyte within the egg chamber. The invariant position of the oocyte is thought to be driven by an upregulation of the adhesion molecule DE-cadherin in the oocyte and the posterior somatic follicle cells, providing the first in vivo example of cell sorting that is specified by...

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PMID: 15852002
DOI: 10.1038/ncb1253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila.PMID 15852002Read ↗

Drosophila oocyte localization is mediated by differential cadherin-based adhesion.Semantic proximity Read ↗

Dystroglycan down-regulation links EGF receptor signaling and anterior-posterior polarity formation in the Drosophila oocyte.Semantic proximity Read ↗

Phenotypic analysis of null mutants for DE-cadherin and Armadillo in Drosophila ovaries reveals distinct aspects of their functions in cell adhesion and cytoskeletal organization.Semantic proximity Read ↗

The Drosophila AP axis is polarised by the cadherin-mediated positioning of the oocyte.Semantic proximity Read ↗

Integrins contribute to the establishment and maintenance of cell polarity in the follicular epithelium of the Drosophila ovarySemantic proximity Read ↗

The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering.Semantic proximity Read ↗

Distinct developmental roles for direct and indirect talin-mediated linkage to actin.Semantic proximity Read ↗

Regulatory mechanisms required for DE-cadherin function in cell migration and other types of adhesion.Semantic proximity Read ↗

Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila.Semantic proximity Read ↗

Talin is required to position and expand the luminal domain of the Drosophila heart tube.Semantic proximity Read ↗

Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis.Semantic proximity Read ↗

Oocyte determination and the origin of polarity in Drosophila: the role of the spindle genes.Semantic proximity Read ↗

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