Article
Conditional switches for extracellular matrix patterning in Drosophila melanogaster.
Genetics - 1 Mar 2008
Khokhar Arvinder, Chen Nan, Yuan Ji-Ping, Li Yishi, Landis Gary N, Beaulieu Gregory, Kaur Harminder, Tower John
Abstract excerpt
An F(1) mutagenesis strategy was developed to identify conditional mutations affecting extracellular matrix (ECM) patterning. Tubulogenesis requires coordinated movement of epithelial cells and deposition of a multilayered ECM. In the Drosophila ovary, an epithelium of follicle cells creates the eggshells, including the paired tubular dorsal appendages (DAs) that act as breathing tubes for the embryo. A P-element...
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