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Article

Talin autoinhibition is required for morphogenesis.

Current biology : CB - 23 Sept 2013

Ellis Stephanie J, Goult Benjamin T, Fairchild Michael J, Harris Nathan J, Long Jenny, Lobo Paolo, Czerniecki Stefan, Van Petegem Filip, Schöck Frieder, Peifer Mark, Tanentzapf Guy

Abstract excerpt

The establishment of a multicellular body plan requires coordinating changes in cell adhesion and the cytoskeleton to ensure proper cell shape and position within a tissue. Cell adhesion to the extracellular matrix (ECM) via integrins plays diverse, essential roles during animal embryogenesis and therefore must be precisely regulated. Talin, a FERM-domain containing protein, forms a direct link between integrin...

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Identifiers

PMID: 24012314
DOI: 10.1016/j.cub.2013.07.054
PMCID: PMC3882074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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