Article
Cbl-Associated Protein CAP contributes to correct formation and robust function of the Drosophila heart tube.
PloS one - 1 Jan 2020
Jammrath Jennifer, Reim Ingolf, Saumweber Harald
Abstract excerpt
The formation of a tube-like structure is a basic step in the making of functional hearts in vertebrates and invertebrates and therefore, its understanding provides important information on heart development and function. In Drosophila, the cardiac tube originates from two bilateral rows of dorsally migrating cells. On meeting at the dorsal midline, coordinated changes in cell shape and adhesive properties...
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