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Article

Apical secretion in epithelial tubes of the Drosophila embryo is directed by the Formin-family protein Diaphanous.

Developmental cell - 1 Jun 2009

Massarwa R'ada, Schejter Eyal D, Shilo Ben-Zion

Abstract excerpt

Apical localization of filamentous actin (F-actin) is a common feature of epithelial tubes in multicellular organisms. However, its origins and function are not known. We demonstrate that the Diaphanous (Dia)/Formin actin-nucleating factor is required for generation of apical F-actin in diverse types of epithelial tubes in the Drosophila embryo. Dia itself is apically localized both at the RNA and protein levels,...

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Identifiers

PMID: 19531358
DOI: 10.1016/j.devcel.2009.04.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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