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Article

Lateral positioning at the dorsal midline: Slit and Roundabout receptors guide Drosophila heart cell migration.

Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 2006

Santiago-Martínez Edgardo, Soplop Nadine H, Kramer Sunita G

Abstract excerpt

Heart morphogenesis requires the coordinated regulation of cell movements and cell-cell interactions between distinct populations of cardiac precursor cells. Little is known about the mechanisms that organize cardiac cells into this complex structure. In this study, we analyzed the role of Slit, an extracellular matrix protein and its transmembrane receptors Roundabout (Robo) and Roundabout2 (Robo2) during...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16888037
DOI: 10.1073/pnas.0605284103
PMCID: PMC1567898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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