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Article

Modeling of the OX1R-orexin-A complex suggests two alternative binding modes.

BMC structural biology - 9 May 2015

Karhu Lasse, Turku Ainoleena, Xhaard Henri

Abstract excerpt

BACKGROUND: Interactions between the orexin peptides and their cognate OX1 and OX2 receptors remain poorly characterized. Site-directed mutagenesis studies on orexin peptides and receptors have indicated amino acids important for ligand binding and receptor activation. However, a better understan...

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Identifiers

PMID: 25957175
DOI: 10.1186/s12900-015-0036-2
PMCID: PMC4469407

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25957175-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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