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Article

Dynein light chain Tctex-type 1 modulates orexin signaling through its interaction with orexin 1 receptor.

PloS one - 1 Jan 2011

Duguay David, Bélanger-Nelson Erika, Mongrain Valérie, Beben Anna, Khatchadourian Armen, Cermakian Nicolas

Abstract excerpt

Orexins (OX-A, OX-B) are neuropeptides involved in the regulation of the sleep-wake cycle, feeding and reward, via activation of orexin receptors 1 and 2 (OX1R, OX2R). The loss of orexin peptides or functional OX2R has been shown to cause the sleep disorder, narcolepsy. Since the regulation of or...

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Identifiers

PMID: 22028875
DOI: 10.1371/journal.pone.0026430
PMCID: PMC3197643

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22028875-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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