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Article

Functional role of a polymorphism in the Pannexin1 gene in collagen-induced platelet aggregation.

Thrombosis and haemostasis - 1 Aug 2015

Molica F, Morel S, Meens M J, Denis J-F, Bradfield P F, Penuela S, Zufferey A, Monyer H, Imhof B A, Chanson M, Laird D W, Fontana P, Kwak B R

Abstract excerpt

Pannexin1 (Panx1) forms ATP channels that play a critical role in the immune response by reinforcing purinergic signal amplification in the immune synapse. Platelets express Panx1 and given the importance of ATP release in platelets, we investigated Panx1 function in platelet aggregation and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25947940
DOI: 10.1160/TH14-11-0981

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25947940-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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