Article

Endothelial pannexin 1 channels control inflammation by regulating intracellular calcium

2019-08-29

Abstract excerpt

<h4>In Brief</h4> Interleukine-1 beta (IL-1β) has been identified as a critical factor that contributes to the inflammatory response in cardiovascular disease (e.g., atherosclerosis). Pannexin 1 (Panx1) channel activity in endothelial cells regulates localized inflammatory cell recruitment. In response to prolonged tumor necrosis factor alpha (TNF) treatment, Yang et al. found that the Panx1 channel is targeted t...

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Literature Corpus work: 7146cd5b-5e0d-5c3e-bb68-b5eec79fadf4
DOI: 10.1101/750323

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