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Identification of a Novel Rat NR2B Subunit Gene Promoter Region Variant and Its Association with Microwave-Induced Neuron Impairment.

Molecular neurobiology - 1 May 2016

Wang Li-Feng, Tian Da-Wei, Li Hai-Juan, Gao Ya-Bing, Wang Chang-Zhen, Zhao Li, Zuo Hong-Yan, Dong Ji, Qiao Si-Mo, Zou Yong, Xiong Lu, Zhou Hong-Mei, Yang Yue-Feng, Peng Rui-Yun, Hu Xiang-Jun

Abstract excerpt

Microwave radiation has been implicated in cognitive dysfunction and neuronal injury in animal models and in human investigations; however, the mechanism of these effects is unclear. In this study, single nucleotide polymorphism (SNP) sites in the rat GRIN2B promoter region were screened. The associations of these SNPs with microwave-induced rat brain dysfunction and with rat pheochromocytoma-12 (PC12) cell...

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PMID: 25917873
DOI: 10.1007/s12035-015-9169-3

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