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Article

Association between a polymorphism in the promoter of a glutamate receptor subunit gene (GRIN2A) and alcoholism.

Addiction biology - 1 Jul 2012

Domart Marie-Charlotte, Benyamina Amine, Lemoine Antoinette, Bourgain Catherine, Blecha Lisa, Debuire Brigitte, Reynaud Michel, Saffroy Raphaël

Abstract excerpt

A variable (GT)(n) repeat in the 5'-regulatory region of N-methyl-D-aspartate GRIN2A subtype has recently been identified and associated with psychiatric disorders. In this study, we examined the association of this polymorphism with alcohol dependence. Subject-control analysis included 206 alcohol-dependent and 168 control subjects. Average observed repeat numbers and genotype distributions were significantly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Receptors, N-Methyl-D-Aspartate

Source

Identifiers

PMID: 21507155
DOI: 10.1111/j.1369-1600.2011.00321.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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