Article
Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes.
The European journal of neuroscience - 1 Sept 2007
Niemann Stephan, Kanki Hiroaki, Fukui Yasuyuki, Takao Keizo, Fukaya Masahiro, Hynynen Meri N, Churchill Michael J, Shefner Jeremy M, Bronson Roderick T, Brown Robert H, Watanabe Masahiko, Miyakawa Tsuyoshi, Itohara Shigeyoshi, Hayashi Yasunori
Abstract excerpt
NR3B is a modulatory subunit of the NMDA receptor, abundantly expressed in both cranial and spinal somatic motoneurons and at lower levels in other regions of the brain as well. Recently, we found the human NR3B gene (GRIN3B) to be highly genetically heterogeneous, and that approximately 10% of t...
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