Article
An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray.
European journal of human genetics : EJHG - 1 Jul 2005
Qin Shengying, Zhao Xu, Pan Yuxi, Liu Jianhua, Feng Guoyin, Fu Jingchun, Bao Jiying, Zhang Zhizhou, He Lin
Abstract excerpt
Dysfunction of the N-methyl-D-aspartate (NMDA) receptors has been implicated in the etiology of schizophrenia based on psychotomimetic properties of several antagonists and on observation of genetic animal models. To conduct association analysis of the NMDA receptors in the Chinese population, we examined 16 reported SNPs across the NMDA receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B), five of...
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