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Article

Identification of a novel variant of the human NR2B gene promoter region and its possible association with schizophrenia.

Molecular psychiatry - 1 Jan 2002

Miyatake R, Furukawa A, Suwaki H

Abstract excerpt

N-methyl-D-aspartate (NMDA) receptor dysfunction is involved in the pathogenesis of schizophrenia. We determined the nucleotide sequence of the 5'-upstream region of the human NMDA receptor 2B (NR2B) subunit gene and identified a novel T-200G variant located in one of the Sp1 binding sites. To investigate the effect of this variant on the transcriptional activity of the hNR2B gene, we performed gene reporter...

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Identifiers

PMID: 12476325
DOI: 10.1038/sj.mp.4001152

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NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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