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Article

Early activated hepatic stellate cell-derived molecules reverse acute hepatic injury.

World journal of gastroenterology - 14 Apr 2015

Chang Wen-Ju, Song Lu-Jun, Yi Tuo, Shen Kun-Tang, Wang Hong-Shan, Gao Xiao-Dong, Li Min, Xu Jian-Min, Niu Wei-Xin, Qin Xin-Yu

Abstract excerpt

AIM: To test whether hepatic stellate cells (HSCs) at different activation stages play different roles in acetaminophen (APAP)-induced acute liver injury (ALI). METHODS: HSCs were isolated from mouse liver and cultured in vitro. Morphological changes of initiation HSCs [HSCs (5d)] and perpetuation HSCs [HSCs (p3)] were observed by immunofluorescence and transmission electron microscopy. The protective effects of...

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Identifiers

PMID: 25892868
DOI: 10.3748/wjg.v21.i14.4184
PMCID: PMC4394079

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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