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Article

Modified autonomic regulation in mice mutated in the β4 subunit of the lh/lh calcium channel.

Biochemical and biophysical research communications - 29 May 2015

Murakami Manabu, Suzuki Takashi, Wu Tsai-Wen, Kuwasako Kenji, Takahashi Eiki, Watanabe Hiroyuki, Murakami Agnieszka M, Miyoshi Ichiro, Yanagisawa Teruyuki, Sasano Hironobu, Ono Kyoichi, Ohba Takayoshi

Abstract excerpt

Genetic analyses have revealed an important association between P/Q-type calcium channel activities and hereditary neurological disorders. The P/Q-type channels are composed principally of heterologous multimeric subunits including CaV2.1 and CaVβ4. Of these, the β4 subunit is thought to play a significant role in channel physiology, because a mouse line mutant in that subunit (the lethargic mouse: lh) exhibits a...

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PMID: 25892515
DOI: 10.1016/j.bbrc.2015.03.112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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