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Article

Familial hypertrophic cardiomyopathy mice display gender differences in electrophysiological abnormalities.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing - 1 Mar 1998

Berul C I, Christe M E, Aronovitz M J, Maguire C T, Seidman C E, Seidman J G, Mendelsohn M E

Abstract excerpt

Genetically-manipulated mice harboring an alpha-myosin heavy chain Arg403Gln missense mutation (alpha-MHC403/+) display a phenotype characteristic of familial hypertrophic cardiomyopathy (FHC). Male and female (30 +/- 8 week old) heterozygous alpha-MHC403/+ mice and litter-mate controls were evaluated using a surface electrocardiogram (ECG) and an in vivo cardiac electrophysiology study (EPS). Wild type animals...

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Identifiers

PMID: 9869991
DOI: 10.1023/a:1009700404218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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