Article
Modified autonomic regulation in mice with a P/Q-type calcium channel mutation.
Biochemical and biophysical research communications - 27 Mar 2009
Ohba Takayoshi, Takahashi Eiki, Murakami Manabu
Abstract excerpt
Recent genetic analyses revealed an important association between P/Q-type channels and hereditary neurological disorders. The alpha1 subunit of P/Q-type channels is coded by a single CaV2.1 gene. Since calcium entry via neuronal calcium channels is essential for neurotransmission, P/Q-type channels may play an important role in cardiac autonomic neurotransmission. To elucidate the physiological importance of...
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