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Article

Cardiac Arrhythmias: From (Transgenic) Mice to Men

1 Sept 2001

Abstract excerpt

Transgenic and gene-targeted mice now are frequently used to study cardiac arrhythmias due to the ease with which the mouse genome can be manipulated. Marked electrophysiologic differences are present between the mouse and human heart, however, and the utility of the mouse as a model for arrhythmias and sudden death remains controversial. Tachyarrhythmias, bradyarrhythmias, and ECG in the mouse need to be...

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PMID: 11573703
DOI: 10.1046/j.1540-8167.2001.01089.x

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