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Article

Opposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progression

14 Apr 2015

Abstract excerpt

BACKGROUND: Among women worldwide, breast cancer is the most commonly diagnosed cancer, and the second leading cause of cancer-related deaths. Improved understanding of breast tumourigenesis may facilitate the development of more effective therapies. Peroxisome proliferator-activated receptor (PPAR)γ is a transcription factor that regulates genes involved in insulin sensitivity and adipogenesis. Previously, we...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 25889730
DOI: 10.1186/s12943-015-0347-8

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