Article

Tumor Necrosis Factor Receptor Signaling Modulates Carcinogenesis in a Mouse Model of Breast Cancer

2020-03-13

Abstract excerpt

Proinflammatory conditions have long been associated with mammary carcinogenesis and breast cancer progression. The underlying mechanisms are incompletely understood but signaling of TNFα through its receptors TNFR1 and TNFR2 is a major mediator of inflammation in both, obesity and in the response of tissues to radiation, two known risk factors for the development of breast cancer. Using the MMTV-Wnt1 mouse model...

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Literature Corpus work: 0b4ec96a-17ee-5e7a-8c7a-d2d48f7d2f42
DOI: 10.1101/2020.03.12.989335

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