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Article

TP53 R72P polymorphism modulates DNA methylation in hepatocellular carcinoma.

Molecular cancer - 2 Apr 2015

Rebbani Khadija, Marchio Agnès, Ezzikouri Sayeh, Afifi Rajaa, Kandil Mostafa, Bahri Olfa, Triki Henda, El Feydi Abdellah Essaid, Dejean Anne, Benjelloun Soumaya, Pineau Pascal

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by widespread epidemiological and molecular heterogeneity. Previous work showed that in the western part of North Africa, a region of low incidence of HCC, mutations are scarce for this tumor type. As epigenetic changes are considered possible surrogates to mutations in human cancers, we decided, thus, to characterize DNA methylation in HCC from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25889455
DOI: 10.1186/s12943-015-0340-2
PMCID: PMC4393630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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