Article
Frequent loss of p53 codon 72 Pro variant in hepatitis C virus-positive carriers with hepatocellular carcinoma.
Cancer letters - 25 Apr 2003
Anzola Mónica, Cuevas Nerea, López-Martínez Mónica, Saiz Alberto, Burgos Juan José, de Pancorbo Marian Martínez
Abstract excerpt
Codon 72 exon 4 polymorphism of the p53 gene has been implicated in cancer risk and it has been suggested that it may have an impact on the clinical outcome of the disease. Our objective was to evaluate the association between p53 polymorphism at codon 72 and hepatocellular carcinoma. The p53 codon 72 genotype was examined in 97 biopsy samples from 67 Basque patients histologically diagnosed with hepatocellular...
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