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Article

Polymorphisms in the Haem Oxygenase-1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children.

Malaria journal - 11 Apr 2015

Hansson Helle H, Maretty Lasse, Balle Christina, Goka Bamenla Q, Luzon Elisa, Nkrumah Francis N, Schousboe Mette L, Rodrigues Onike P, Bygbjerg Ib Christian, Kurtzhals Jørgen A L, Alifrangis Michael, Hempel Casper

Abstract excerpt

BACKGROUND: Haem oxygenase-1 (HO-1) catabolizes haem and has both cytotoxic and cytoprotective effects. Polymorphisms in the promoter of the Haem oxygenase-1 (HMOX1) gene encoding HO-1 have been associated with several diseases including severe malaria. The objective of this study was to determine the allele and genotype frequencies of two single nucleotide polymorphisms; A(-413)T and G(-1135)A, and a (GT)n...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25888733
DOI: 10.1186/s12936-015-0668-5
PMCID: PMC4396170

Genes

HMOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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