Article
Polymorphisms in interleukin-1beta and interleukin-1 receptor antagonist genes and malaria in Ghanaian children.
Scandinavian journal of immunology - 1 Dec 2002
Gyan B, Goka B, Cvetkovic J T, Perlmann H, Lefvert A-K, Akanmori B, Troye-Blomberg M
Abstract excerpt
We have investigated the possible associations between polymorphisms in two interleukin-1 (IL-1) genes and severity of Plasmodium falciparum malaria in Ghanaian children with cerebral malaria, severe anaemia or uncomplicated malaria and controls. There was no significant difference in genotype and allele frequencies in IL-1beta exon 5 or interleukin-1 receptor antagonist (IL-1ra) polymorphisms between the studied...
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