Article
Study on association between genetic polymorphisms of haem oxygenase-1, tumour necrosis factor, cadmium exposure and malaria pathogenicity and severity.
Malaria journal - 17 Sept 2010
Kuesap Jiraporn, Hirayama Kenji, Kikuchi Mihoko, Ruangweerayut Ronnatrai, Na-Bangchang Kesara
Abstract excerpt
BACKGROUND: Malaria is the most important public health problems in tropical and sub-tropical countries. Haem oxygenase (HO) enzyme and the pro-inflammatory cytokine tumour necrosis factor (TNF) have been proposed as one of the factors that may play significant role in pathogenicity/severity of malaria infection. HO is the enzyme of the microsomal haem degradation pathway that yields biliverdin, carbon monoxide,...
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