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Article

iNOS promoter variants and severe malaria in Ghanaian children.

Tropical medicine & international health : TM & IH - 1 Oct 2004

Cramer Jakob P, Mockenhaupt Frank P, Ehrhardt Stephan, Burkhardt Jana, Otchwemah Rowland N, Dietz Ekkehardt, Gellert Sabine, Bienzle Ulrich

Abstract excerpt

Nitric oxide is an important mediator in the host defence against Plasmodium falciparum malaria. It has antiparasitic effects in vitro. However, its role in clinical disease remains controversial. Polymorphisms in the inducible nitric oxide synthase promoter (iNOS; -954G-->C, -1173C-->T, -2.6 kb CCTTT(n) microsatellite) may influence susceptibility to and severity of malaria. We tested this hypothesis in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15482399
DOI: 10.1111/j.1365-3156.2004.01312.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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