Article
A new platform for ultra-high density Staphylococcus aureus transposon libraries.
BMC genomics - 29 Mar 2015
Santiago Marina, Matano Leigh M, Moussa Samir H, Gilmore Michael S, Walker Suzanne, Meredith Timothy C
Abstract excerpt
BACKGROUND: Staphylococcus aureus readily develops resistance to antibiotics and achieving effective therapies to overcome resistance requires in-depth understanding of S. aureus biology. High throughput, parallel-sequencing methods for analyzing transposon mutant libraries have the potential to revolutionize studies of S. aureus, but the genetic tools to take advantage of the power of next generation sequencing...
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