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Genes Influencing Phage Host Range in Staphylococcus aureus on a Species-Wide Scale.

mSphere - 13 Jan 2021

Moller Abraham G, Winston Kyle, Ji Shiyu, Wang Junting, Hargita Davis Michelle N, Solís-Lemus Claudia R, Read Timothy D

Abstract excerpt

Staphylococcus aureus is a human pathogen that causes serious diseases, ranging from skin infections to septic shock. Bacteriophages (phages) are both natural killers of S. aureus, offering therapeutic possibilities, and important vectors of horizontal gene transfer (HGT) in the species. Here, we used high-throughput approaches to understand the genetic basis of strain-to-strain variation in sensitivity to...

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Identifiers

PMID: 33441407
DOI: 10.1128/mSphere.01263-20
PMCID: PMC7845607

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