Article

Dual transposon sequencing (Dual Tn-seq) to probe genome-wide genetic interactions

2024-09-25

Abstract excerpt

<h4>ABSTRACT</h4> Understanding gene function on a genome-wide scale is a fundamental goal in biology. With the advent of next-generation sequencing, high-throughput methods such as transposon sequencing (Tn- seq) were developed to measure fitness of single deletion mutants en masse. Nevertheless, gene redundancy complicates these approaches, as inactivating genes individually may not produce discernable phenotyp...

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Literature Corpus work: 20fc7ee8-4b10-57f8-9db3-946d3cd6256b
DOI: 10.1101/2024.09.24.614635

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