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Article

Near full length hepatitis C virus genome reconstruction by next generation sequencing based on genotype-independent amplification.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jul 2015

Bartolini Barbara, Giombini Emanuela, Abbate Isabella, Selleri Marina, Rozera Gabriella, Biagini Tommaso, Visco-Comandini Ubaldo, Taibi Chiara, Capobianchi Maria Rosaria

Abstract excerpt

BACKGROUND: Deep sequencing has a deep impact on the study of rapidly mutating RNA viruses, such as hepatitis C virus, proving to be an invaluable tool for analyzing virus diversity and evolution. AIM: Genotype-independent high-throughput pyrosequencing was used to obtain near full length hepatitis C virus genome sequence reconstruction directly from clinical samples. METHODS: Samples from hepatitis C virus...

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Share to DNA, Viral
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

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Source

Identifiers

PMID: 25888234
DOI: 10.1016/j.dld.2015.03.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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