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Article

Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus.

BMC infectious diseases - 3 Sept 2018

Soria María Eugenia, Gregori Josep, Chen Qian, García-Cehic Damir, Llorens Meritxell, de Ávila Ana I, Beach Nathan M, Domingo Esteban, Rodríguez-Frías Francisco, Buti María, Esteban Rafael, Esteban Juan Ignacio, Quer Josep, Perales Celia

Abstract excerpt

BACKGROUND: Despite the high sustained virological response rates achieved with current directly-acting antiviral agents (DAAs) against hepatitis C virus (HCV), around 5-10% of treated patients do not respond to current antiviral therapies, and basal resistance to DAAs is increasingly detected among treatment-naïve infected individuals. Identification of amino acid substitutions (including those in minority...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30176817
DOI: 10.1186/s12879-018-3356-6
PMCID: PMC6122477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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