Article
A method for near full-length amplification and sequencing for six hepatitis C virus genotypes.
BMC genomics - 17 Mar 2016
Bull Rowena A, Eltahla Auda A, Rodrigo Chaturaka, Koekkoek Sylvie M, Walker Melanie, Pirozyan Mehdi R, Betz-Stablein Brigid, Toepfer Armin, Laird Melissa, Oh Steve, Heiner Cheryl, Maher Lisa, Schinkel Janke, Lloyd Andrew R, Luciani Fabio
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) is a rapidly evolving RNA virus that has been classified into seven genotypes. All HCV genotypes cause chronic hepatitis, which ultimately leads to liver diseases such as cirrhosis. The genotypes are unevenly distributed across the globe, with genotypes 1 and 3 being the most prevalent. Until recently, molecular epidemiological studies of HCV evolution within the host and at...
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