Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes.

doi:10.1128/JCM.00330-16

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes.

Journal of clinical microbiology - 1 Oct 2016

Thomson Emma, Ip Camilla L C, Badhan Anjna, Christiansen Mette T, Adamson Walt, Ansari M Azim, Bibby David, Breuer Judith, Brown Anthony, Bowden Rory, Bryant Josie, Bonsall David, Da Silva Filipe Ana, Hinds Chris, Hudson Emma, Klenerman Paul, Lythgow Kieren, Mbisa Jean L, McLauchlan John, Myers Richard, Piazza Paolo, Roy Sunando, Trebes Amy, Sreenu Vattipally B, Witteveldt Jeroen, Barnes Eleanor, Simmonds Peter

Abstract excerpt

Affordable next-generation sequencing (NGS) technologies for hepatitis C virus (HCV) may potentially identify both viral genotype and resistance genetic motifs in the era of directly acting antiviral (DAA) therapies. This study compared the ability of high-throughput NGS methods to generate full-length, deep, HCV sequence data sets and evaluated their utility for diagnostics and clinical assessment. NGS methods...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Viral

Share to Genotype

Share to Hepacivirus

Share to Hepatitis C

Share to High-Throughput Nucleotide Sequencing

Share to Sequence Analysis, DNA

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 27385709
DOI: 10.1128/JCM.00330-16
PMCID: PMC5035407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes.PMID 27385709Read ↗

Clinical evaluation of a Hepatitis C Virus whole-genome sequencing pipeline for genotyping and resistance testing.Semantic proximity Read ↗

Next-Generation Sequencing Methods for Sensitive Hepatitis B Viral Genome Analysis: A European Study.Semantic proximity Read ↗

Hepatitis C virus deep sequencing for sub-genotype identification in mixed infections: A real-life experience.Semantic proximity Read ↗

Technical Validation of a Hepatitis C Virus Whole Genome Sequencing Assay for Detection of Genotype and Antiviral Resistance in the Clinical PathwaySemantic proximity Read ↗

Whole genome sequencing of hepatitis C virus from dried blood spots by hybrid capture for genotype and antiviral resistance determination.Semantic proximity Read ↗

Genotype- and Subtype-Independent Full-Genome Sequencing Assay for Hepatitis C VirusSemantic proximity Read ↗

Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus.Semantic proximity Read ↗

Advanced molecular surveillance approaches for characterization of blood borne hepatitis viruses.Semantic proximity Read ↗

Validation of a Genotype-Independent Hepatitis C Virus Near-Whole Genome Sequencing Assay.Semantic proximity Read ↗

Applications of next-generation sequencing technologies to diagnostic virology.Semantic proximity Read ↗

High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods.Semantic proximity Read ↗

A near full-length open reading frame next generation sequencing assay for genotyping and identification of resistance-associated variants in hepatitis C virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.