Article
Hepatitis C virus deep sequencing for sub-genotype identification in mixed infections: A real-life experience.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Feb 2018
Del Campo José A, Parra-Sánchez Manuel, Figueruela Blanca, García-Rey Silvia, Quer Josep, Gregori Josep, Bernal Samuel, Grande Lourdes, Palomares José C, Romero-Gómez Manuel
Abstract excerpt
BACKGROUND: The effectiveness of the new generation of hepatitis C treatments named direct-acting antiviral agents (DAAs) depends on the genotype, subtype, and resistance-associated substitutions present in individual patients. The aim of this study was to evaluate a massive sequencing platform for the analysis of genotypes and subtypes of hepatitis C virus (HCV) in order to optimize therapy. METHODS: A total of...
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