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Genotype- and Subtype-Independent Full-Genome Sequencing Assay for Hepatitis C Virus

16 Apr 2015

Abstract excerpt

Hepatitis C virus (HCV) exhibits a high genetic diversity and is classified into 6 genotypes, which are further divided into 66 subtypes. Current sequencing strategies require prior knowledge of the HCV genotype and subtype for efficient amplification, making it difficult to sequence samples with a rare or unknown genotype and/or subtype. Here, we describe a subtype-independent full-genome sequencing assay based...

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PMID: 25878342
DOI: 10.1128/jcm.02624-14

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