Article
Improved Tacrolimus Target Concentration Achievement Using Computerized Dosing in Renal Transplant Recipients--A Prospective, Randomized Study.
Transplantation - 1 Oct 2015
Størset Elisabet, Åsberg Anders, Skauby Morten, Neely Michael, Bergan Stein, Bremer Sara, Midtvedt Karsten
Abstract excerpt
BACKGROUND: Early after renal transplantation, it is often challenging to achieve and maintain tacrolimus concentrations within the target range. Computerized dose individualization using population pharmacokinetic models may be helpful. The objective of this study was to prospectively evaluate the target concentration achievement of tacrolimus using computerized dosing compared with conventional dosing performed...
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