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Recent insights into C3 glomerulopathy

10 Mar 2013

Abstract excerpt

'C3 glomerulopathy' is a recent disease classification comprising several rare types of glomerulonephritis (GN), including dense deposit disease (DDD), C3 glomerulonephritis (C3GN) and CFHR5 nephropathy. These disorders share the key histological feature of isolated complement C3 deposits in the glomerulus. A common aetiology involving dysregulation of the alternative pathway (AP) of complement has been...

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PMID: 23479095
DOI: 10.1093/ndt/gfs430

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