Article
The role of the alternative pathway of complement activation in glomerular diseases.
Clinical and experimental medicine - 1 Aug 2018
Łukawska Emilia, Polcyn-Adamczak Magdalena, Niemir Zofia I
Abstract excerpt
The complement system (CS) has recently been recognized as a bridge between innate and adaptive immunity that constitutes a very complex mechanism controlling the clearance of pathogens, cellular debris, and immune complexes. Out of three known pathways of complement activation, the alternative pathway (AP) plays a critical role in host defense by amplifying the complement response, independently of initiation...
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