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Article

Loss of Dgcr8-mediated microRNA expression in the kidney results in hydronephrosis and renal malformation.

BMC nephrology - 14 Apr 2015

Bartram Malte P, Dafinger Claudia, Habbig Sandra, Benzing Thomas, Schermer Bernhard, Müller Roman-Ulrich

Abstract excerpt

BACKGROUND: Small non-coding RNA molecules (miRNAs) play a pivotal role in regulating gene expression in development. miRNAs regulate key processes at the cellular level and thereby influence organismal and tissue development including kidney morphogenesis. A miRNA molecule is initially synthesized as a longer hairneedle-shaped RNA transcript and then processed through an enzymatic complex that contains the...

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Identifiers

PMID: 25881298
DOI: 10.1186/s12882-015-0053-1
PMCID: PMC4445526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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