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Article

Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival

1 Oct 2015

Abstract excerpt

MicroRNAs are small noncoding RNAs that post-transcriptionally regulate mRNA levels. While previous studies have demonstrated that miRNAs are indispensable in the nephron progenitor and ureteric bud lineage, little is understood about stromal miRNAs during kidney development. The renal stroma (marked by expression of FoxD1) gives rise to the renal interstitium, a subset of peritubular capillaries, and multiple...

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PMID: 26438731
DOI: 10.14814/phy2.12537

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