Article
Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury.
Journal of the American Society of Nephrology : JASN - 1 Nov 2008
Ho Jacqueline, Ng Kar Hui, Rosen Seymour, Dostal Ales, Gregory Richard I, Kreidberg Jordan A
Abstract excerpt
MicroRNAs (miRNAs) are in a class of endogenous, small, noncoding RNAs that exert their effects through posttranscriptional repression of specific target mRNAs. Although miRNAs have been implicated in the regulation of diverse biologic processes, little is known about miRNA function in the kidney...
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